Hi, dear subscribers and readers. It has been almost 3 years since we published our July 2023 article, “HGH Therapy and the Menstrual Cycle: The Impact of Human Growth Hormone.”
However, we continue to receive many questions on this topic, which is why we decided to create Part 2 — a more detailed and expanded version focused on women’s health, well-being, and a deeper understanding of this important subject.
How does HGH affect the menstrual cycle?
In general, Human Growth Hormone (HGH) may positively influence overall hormonal balance when there is an imbalance of key hormones. It can indirectly affect the body’s hormonal architecture, which in some cases may support women’s overall health, well-being, and physiological balance.
HGH therapy itself is not a direct regulator of the menstrual cycle. However, through its influence on overall hormonal balance and Insulin-like Growth Factor 1 (IGF-1), it may in some cases affect the menstrual cycle. In some women, the cycle may become more regular, while in others certain changes may be noticed.
When menstrual cycles improve, this is often linked to HGH’s indirect effects on the body’s hormonal environment. For example, if hormonal imbalances existed before therapy, improvements in metabolism, insulin sensitivity, or IGF-1 levels may sometimes help stabilize the hormonal system. However, this is highly individual and not guaranteed for everyone. It should be viewed as a possible indirect effect rather than the primary function of HGH therapy.
How Does HGH Impact Estrogen and Progesterone?
Human Growth Hormone (HGH) does not directly regulate estrogen or progesterone. However, it may indirectly influence overall hormonal balance through its effects on metabolism and Insulin-like Growth Factor 1 (IGF-1). As a result, when the hormonal system is out of balance, HGH may in some cases help support stabilization of the overall hormonal environment, which can indirectly affect female hormones as well.
The menstrual cycle begins when the hypothalamus releases hormones that stimulate the pituitary gland. The pituitary gland then produces Follicle-Stimulating Hormone (FSH), which stimulates the growth of follicles in the ovaries. One of these follicles matures and produces estrogen.
When estrogen levels become high enough, a surge of Luteinizing Hormone (LH) is triggered, leading to ovulation. During ovulation, the egg is released from the follicle. After this, the follicle transforms into the corpus luteum, which produces progesterone.
If fertilization does not occur, estrogen and progesterone levels begin to drop. As a result, the uterine lining (endometrium) breaks down and sheds, which causes menstruation (the menstrual period).
Can HGH Improve Libido in Women?
During ovulation, estrogen levels rise because the growing follicle in the ovary produces estrogen to prepare the body for ovulation. After ovulation, the follicle transforms into the corpus luteum, which produces progesterone. Progesterone is needed to support the uterine lining in case fertilization occurs. In this way, estrogen prepares the body for ovulation, while progesterone prepares the uterus for possible implantation. This is all part of the body’s natural cyclical hormonal process.
Human Growth Hormone (HGH) does not directly increase testosterone levels. However, through its influence on overall hormonal balance, metabolism, and recovery, HGH may in some cases indirectly contribute to a slight increase in testosterone activity or libido in women. When this happens, some women may notice an improvement in sexual desire and overall well-being during therapy. However, this is not the primary purpose of HGH therapy, and results can vary from person to person.
Should HGH Therapy Be Stopped During the Menstrual Cycle?
No, it is not necessary to stop. In fact, continuing growth hormone therapy during menstruation helps maintain a balanced hormone environment. Therefore, stopping is not required and, in many cases, it is even recommended.
It is important to monitor individual responses to HGH therapy, especially related to menstrual cycles and hormonal fluctuations. Anyone experiencing irregular or unexpected changes in their menstrual cycles during HGH therapy should consult their healthcare professional or endocrinologist for personalized advice.
We would like to thank endocrinologist Dr. Melissa Wong from HGH Singapore Wellness Clinic for helping prepare this article
